Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NMT1 | P30419 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509495 | 0.90 | FFAR4 (0.60) | KMT2ANMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16502945 | 0.81 | LMNA (0.60) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16502982 | 0.81 | KMT2A (0.58) | KMT2ANMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13457978 | 0.80 | LMNA (0.66) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16502939 | 0.80 | NMT1 (0.65) | KMT2ANMT1SMN1; SMN2L3MBTL1EDNRB | |
| SCHEMBL16502974 | 0.79 | L3MBTL1 (0.57) | KMT2ANMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16817058 | 0.78 | LMNA (0.71) | KMT2ANMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16502937 | 0.77 | KMT2A (0.57) | KMT2ANMT1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL16503036 | 0.76 | LMNA (0.61) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16502962 | 0.76 | NMT1 (0.65) | NMT1LMNAHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828346-B2 | N-myristoyl transferase inhibitors | UNIVERSITY OF DUNDEE (GB) | 2017-11-28 | — | — | US | disclosed |
| US-9828346-B2 | N-myristoyl transferase inhibitors | UNIVERSITY OF DUNDEE (GB) | 2017-11-28 | — | — | US | disclosed |
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIVERSITY OF DUNDEE (GB) | 2016-03-03 | — | — | US | disclosed |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIVERSITY OF DUNDEE (GB) | 2016-03-03 | — | — | US | disclosed |
| US-9156811-B2 | N-myristoyl transferase inhibitors | Univeristy of Dundee (GB) | 2015-10-13 | — | — | US | disclosed |
| US-9156811-B2 | N-myristoyl transferase inhibitors | Univeristy of Dundee (GB) | 2015-10-13 | — | — | US | disclosed |
| EP-2323987-B1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIV DUNDEE (GB) | 2015-06-24 | — | — | EP | disclosed |
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | DUNDEE, UNIVERSITY OF (GB) | 2011-12-22 | — | — | US | disclosed |
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | DUNDEE, UNIVERSITY OF (GB) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | GNMT, NNMT, SPTLC1 | KMT2A 1145/4885NMT1 13/4885LMNA 4097/4885 |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | GNMT, NNMT, SPTLC1 | KMT2A 1145/4885NMT1 13/4885LMNA 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.