Oxendolone

Oxendolone

SCHEMBL1650323

CCC1C[C@H]2C3CCC4=CC(=O)CCC4[C@H]3CCC2(C)[C@H]1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 3/20 0.74
▸ SHBG P04278 3/20 0.66
▸ SERPINA6 P08185 2/20 0.66
▸ ALDH1A1 P00352 2/20 0.66
▸ SLC22A1 O15245 1/20 0.66
▸ THRB P10828 1/20 0.66
▸ CYP19A1 P11511 2/20 0.57
▸ LMNA P02545 5/20 0.53
▸ MAPT P10636 1/20 0.53
▸ CYP3A4 P08684 4/20 0.52
▸ ABCB11 O95342 3/20 0.52
▸ SLC6A4 P31645 3/20 0.52
▸ CYP2C19 P33261 2/20 0.52
▸ ESR1 P03372 2/20 0.52
▸ NR3C1 P04150 2/20 0.52
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ TSHR P16473 1/20 0.52
▸ HIF1A Q16665 1/20 0.52
▸ ADRA2A P08913 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxendolone SCHEMBL233297 1.00 PGR (0.74) PGRSHBGSERPINA6ALDH1A1SLC22A1
Oxendolone SCHEMBL12826307 1.00 PGR (0.74) PGRSHBGSERPINA6ALDH1A1SLC22A1
Oxendolone SCHEMBL10380170 1.00 PGR (0.74) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL10380864 0.91 PGR (0.66) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL10624478 0.86 ALDH1A1 (0.72) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL17209910 0.86 SHBG (0.72) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL17078378 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL21010519 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL4660380 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL14870642 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569868-B2 Apparatuses and methods for enhancing a reliability of power available to communicaton devices via an insulator AT&T INTELLECTUAL PROPERTY I, L.P. (US) 2023-01-31 — — US disclosed
US-20220302958-A1 APPARATUSES AND METHODS FOR ENHANCING A RELIABILITY OF POWER AVAILABLE TO COMMUNICATON DEVICES VIA AN INSULATOR AT&T INTELLECTUAL PROPERTY I, L.P. (US) 2022-09-22 — — US disclosed
US-20220302950-A1 APPARATUSES AND METHODS FOR FACILITATING A CONVEYANCE OF STATUS IN COMMUNICATION SYSTEMS AND NETWORKS AT&T INTELLECTUAL PROPERTY I, L.P. (US) 2022-09-22 — — US disclosed
US-20200155521-A1 PHARMACEUTICAL COMBINATION FOR TREATMENT OF CANCER ARQULE, INC. 2020-05-21 — — US disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 — — US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200155521-A1 PHARMACEUTICAL COMBINATION FOR TREATMENT OF CANCER TP53, KRAS, VHL PGR 1396/4885SHBG 2973/4885SERPINA6 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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