Oxendolone

Oxendolone

SCHEMBL233297

CC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]2(C)[C@H]1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 3/20 0.74
▸ SHBG P04278 3/20 0.66
▸ SERPINA6 P08185 2/20 0.66
▸ ALDH1A1 P00352 2/20 0.66
▸ SLC22A1 O15245 1/20 0.66
▸ THRB P10828 1/20 0.66
▸ CYP19A1 P11511 2/20 0.57
▸ LMNA P02545 5/20 0.53
▸ MAPT P10636 1/20 0.53
▸ CYP3A4 P08684 4/20 0.52
▸ ABCB11 O95342 3/20 0.52
▸ SLC6A4 P31645 3/20 0.52
▸ CYP2C19 P33261 2/20 0.52
▸ ESR1 P03372 2/20 0.52
▸ NR3C1 P04150 2/20 0.52
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ TSHR P16473 1/20 0.52
▸ HIF1A Q16665 1/20 0.52
▸ ADRA2A P08913 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxendolone SCHEMBL12826307 1.00 PGR (0.74) PGRSHBGSERPINA6ALDH1A1SLC22A1
Oxendolone SCHEMBL1650323 1.00 PGR (0.74) PGRSHBGSERPINA6ALDH1A1SLC22A1
Oxendolone SCHEMBL10380170 1.00 PGR (0.74) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL10380864 0.91 PGR (0.66) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL10624478 0.86 ALDH1A1 (0.72) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL17209910 0.86 SHBG (0.72) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL17078378 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL21010519 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL4660380 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1
SCHEMBL14870642 0.85 PGR (1.00) PGRSHBGSERPINA6ALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4525938-B1 RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AG (DE) 2026-03-11 — — EP claimed
US-20250319216-A1 RADIOPHARMCEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AG (DE) 2025-10-16 — — US claimed
EP-4608405-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL Veradermics, Incorporated (US) 2025-09-03 — — EP claimed
US-20250262192-A1 PROGNOSTIC PATHWAYS FOR HIGH RISK SEPSIS PATIENTS KONINKLIJKE PHILIPS N.V. (NL) 2025-08-21 — — US claimed
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS INC (US) 2025-07-03 — — US claimed
EP-4525938-A1 RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS Bayer Aktiengesellschaft (DE) 2025-03-26 — — EP claimed
WO-2024091572-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2024-05-02 — — WO claimed
EP-4305206-A1 PROGNOSTIC PATHWAYS FOR HIGH RISK SEPSIS PATIENTS Koninklijke Philips N.V. (NL) 2024-01-17 — — EP claimed
US-11850306-B2 Method for drying hydrogel comprising nanofibrillar cellulose and a dried hydrogel comprising nanofibrillar cellulose UPM-KYMMENE CORPORATION (FI) 2023-12-26 — — US claimed
WO-2023222557-A1 RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2023-11-23 — — WO claimed
EP-0138029-B1 PHARMACEUTICAL COMPOSITION Takeda Chemical Industries, Ltd. (JP) 1992-01-02 — — EP claimed
US-4973469-A ACTIVE MATERIAL ADSORBED ON CROSSLINKED POLYMER, INACTIVE MATERIAL CONTROLS SOLUBILITY ELAN CORPORATION, PLC (IE) 1990-11-27 — — US claimed
EP-0232155-A2 Drug delivery system ELAN CORPORATION PLC (IE) 1987-08-12 — — EP claimed
US-4657901-A MIXTURE OF OXENDOLONE, KERATOLYTIC AGENT AND CARRIER Sheiseido Company, Ltd. (JP) 1987-04-14 — — US claimed
EP-0072662-B1 AQUEOUS SUSPENSION OF OXENDOLONE Takeda Chemical Industries, Ltd. (JP) 1985-05-22 — — EP claimed
EP-0138029-A2 Pharmaceutical composition Takeda Chemical Industries, Ltd. (JP) 1985-04-24 — — EP claimed
US-4462996-A WITH NONIONIC SURFACTANT AND P-HYDROXYBENZOIC ACID ESTER; ANTIANDROGENS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1984-07-31 — — US claimed
EP-0095944-A2 Anti-androgenic preparation for oral cavity administration Takeda Chemical Industries, Ltd. (JP) 1983-12-07 — — EP claimed
EP-0072662-A2 Aqueous suspension of oxendolone Takeda Chemical Industries, Ltd. (JP) 1983-02-23 — — EP claimed
US-4298538-A 16-Dimethylaminomethylene-3-methoxy-1,3,5-(10)-estratrien-17-one, a process for the preparation thereof and its use as a preparative intermediate SCHERING, AKTIENGESELLSCHAFT (DE) 1981-11-03 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER UNG, OGG1, NTPCR PGR 3978/4885SHBG 3358/4885SERPINA6 3185/4885
US-20250319216-A1 RADIOPHARMCEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS KLK3, FOLH1, PSMA2 PGR 773/4885SHBG 4/4885SERPINA6 347/4885
US-20250262192-A1 PROGNOSTIC PATHWAYS FOR HIGH RISK SEPSIS PATIENTS TGFB1, TGFB2, SMAD3 PGR 2891/4885SHBG 55/4885SERPINA6 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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