Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273165 | 1.00 | PGR (1.00) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| SCHEMBL21010519 | 1.00 | PGR (1.00) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| SCHEMBL17078378 | 1.00 | PGR (1.00) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| SCHEMBL14870642 | 1.00 | PGR (1.00) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| SCHEMBL29778360 | 0.91 | PGR (0.84) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| Oxendolone SCHEMBL10380170 | 0.85 | PGR (0.74) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| Oxendolone SCHEMBL233297 | 0.85 | PGR (0.74) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| Oxendolone SCHEMBL1650323 | 0.85 | PGR (0.74) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| Oxendolone SCHEMBL12826307 | 0.85 | PGR (0.74) | PGRSERPINA6SHBGALDH1A1SLC22A1 | |
| SCHEMBL10889253 | 0.83 | PGR (0.72) | PGRSERPINA6SHBGALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020191-B1 | Medicaments for hyperlipidemic and hyperglycemic conditions | COUNCIL SCIENT IND RES (IN) | 2008-12-24 | — | — | EP | disclosed |
| US-6875758-B2 | Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-04-05 | — | — | US | disclosed |
| US-20030216363-A1 | Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2003-11-20 | — | — | US | disclosed |
| US-6579862-B1 | 3B-hydroxy-pregna-5,16-dien-20-one | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2003-06-17 | — | — | US | disclosed |
| EP-1020191-A1 | Medicaments for hypolipidemic and hypoglycemic conditions | Council of Scientific and Industrial Research (IN) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216363-A1 | Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones | CYP27A1, CYP46A1, HSD17B7 | PGR 764/4885SERPINA6 214/4885SHBG 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.