Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755164 | 0.77 | ALDH1A1 (0.50) | ABCB11ALDH1A1L3MBTL1 | |
| SCHEMBL17755166 | 0.77 | L3MBTL1 (0.51) | ABCB11L3MBTL1 | |
| SCHEMBL16956060 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HTTTACR1PTPN1CYP3A4 | |
| SCHEMBL21366670 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HTTTACR1PTPN1CYP3A4 | |
| SCHEMBL2758299 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HTTTACR1PTPN1CYP3A4 | |
| SCHEMBL16284309 | 0.72 | PTGS2 (0.42) | KDM4EL3MBTL1PTGS2 | |
| SCHEMBL15695556 | 0.72 | PTGS2 (0.42) | KDM4EL3MBTL1PTGS2 | |
| SCHEMBL16953674 | 0.72 | ABCB11 (0.37) | ABCB11ALDH1A1HTTTACR1PTPN1 | |
| SCHEMBL9119439 | 0.72 | CYP3A4 (0.38) | ALDH1A1TACR1PTPN1CYP3A4KDM4E | |
| SCHEMBL9397903 | 0.71 | ADRB2 (0.39) | ALDH1A1TACR1PTPN1CYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079869-B2 | Chiral disulfonimides | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-20110313150-A1 | CHIRAL DISULFONIMIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313150-A1 | CHIRAL DISULFONIMIDES | STS, SUDS3, SF1 | ABCB11 1433/4885ALDH1A1 86/4885HTT 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.