SCHEMBL16508016

SCHEMBL16508016

C=C[SiH](N)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.31
AKT1 P31749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27486534 0.86 TAAR1 (0.41) ALDH1A1HTT
SCHEMBL10867723 0.74 ALDH1A1 (0.38) TSHRALDH1A1AKT1
SCHEMBL27843739 0.73 HTT (0.36) TSHRALDH1A1HTT
SCHEMBL1712669 0.72 TSHR (0.41) TSHRALDH1A1AKT1
SCHEMBL217350 0.72 TSHR (0.41) TSHRALDH1A1AKT1
Fluoride SCHEMBL27718731 0.70 TSHR (0.39) TSHRALDH1A1AKT1
SCHEMBL1493083 0.69 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL2270554 0.68 ALDH1A1 (0.38) TSHRALDH1A1AKT1
SCHEMBL243791 0.68 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL1066599 0.68 TSHR (0.38) TSHRALDH1A1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015027003-A1 COATING COMPOSITION AND ANTI-SPATTER COATING FORMED THEREFROM ND INDUSTRIES, INC. (US) 2015-02-26 WO disclosed
US-20150056394-A1 Coating Composition and Anti-Spatter Coating Formed Therefrom ND INDUSTRIES, INC. 2015-02-26 US disclosed