SCHEMBL2270554

SCHEMBL2270554

C=C[SiH](Cl)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
AKT1 P31749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27850016 0.97 ALDH1A1 (0.36) ALDH1A1TSHRAKT1
SCHEMBL9064098 0.77 TSHR (0.36) ALDH1A1TSHRAKT1
SCHEMBL27492822 0.75 ACHE (0.38) ALDH1A1
SCHEMBL1712669 0.72 TSHR (0.41) ALDH1A1TSHRAKT1
SCHEMBL217350 0.72 TSHR (0.41) ALDH1A1TSHRAKT1
Fluoride SCHEMBL27718731 0.70 TSHR (0.39) ALDH1A1TSHRAKT1
SCHEMBL6931591 0.70
SCHEMBL3850181 0.69 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL11358171 0.69 AKR1C3 (0.34) ALDH1A1TSHR
SCHEMBL444984 0.69 ALDH1A1 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108865303-A A kind of slurries additive agent and preparation method thereof containing sulfonic acid group 曾来英 2018-11-23 CN claimed
CN-110003265-A A kind of preparation method of 1,4- butine two (trialkyl silyl) ester 珠海市赛纬电子材料股份有限公司 2019-07-12 CN disclosed
CN-103936999-B Silicon-containing compound, solidification compound and solidfied material 株式会社艾迪科 2016-08-17 CN disclosed
CN-103249762-A Addition-curable metallosiloxane compound DAICEL CORP 2013-08-14 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed