Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 11/20 | 0.44 |
| ▸ | NOS2 | P35228 | 11/20 | 0.44 |
| ▸ | NOS3 | P29474 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.36 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508373 | 0.77 | HPGD (0.44) | ALDH1A1NFKB1 | |
| SCHEMBL19526398 | 0.75 | SIGMAR1 (0.57) | NOS1NOS2NOS3ALDH1A1CYP3A4 | |
| SCHEMBL15291795 | 0.74 | NPC1 (0.52) | ALDH1A1SMN1; SMN2CYP3A4SIGMAR1 | |
| SCHEMBL16508323 | 0.74 | ADH1B (0.40) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19526433 | 0.72 | SIGMAR1 (0.43) | ALDH1A1CYP3A4SIGMAR1ESR1ESR2 | |
| SCHEMBL22700148 | 0.72 | ALDH1A1 (0.32) | NOS1NOS2ALDH1A1 | |
| SCHEMBL16508364 | 0.71 | SIGMAR1 (0.62) | NOS1ALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL12168516 | 0.71 | SIGMAR1 (0.38) | SMN1; SMN2SIGMAR1 | |
| SCHEMBL15726519 | 0.71 | NPC1 (0.42) | NOS1NOS3SMN1; SMN2SIGMAR1 | |
| SCHEMBL39710 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | ABCG2, AQP1, AQP3 | NOS1 1062/4885NOS2 1123/4885NOS3 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.