Sugi Predict

Sugi Predict / Compounds / SCHEMBL1650906

SCHEMBL1650906

SCHEMBL1650906

CC(=O)CC(=O)/C=C/c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HAO1 Q9UJM8 1/20 0.70
▸ GLA P06280 1/20 0.62
▸ TDP1 Q9NUW8 1/20 0.62
▸ MAPT P10636 4/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ PLIN1 O60240 2/20 0.61
▸ LMNA P02545 2/20 0.61
▸ RECQL P46063 2/20 0.61
▸ PLIN5 Q00G26 2/20 0.61
▸ ABHD5 Q8WTS1 2/20 0.61
▸ CYP1A2 P05177 1/20 0.61
▸ CYP2D6 P10635 1/20 0.61
▸ CYP2C9 P11712 1/20 0.61
▸ F3 P13726 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ KMT2A Q03164 2/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ RAB9A P51151 1/20 0.58
▸ KCNH2 Q12809 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1650908 1.00 HAO1 (0.70) HAO1GLATDP1MAPTALDH1A1
SCHEMBL316674 0.90 HAO1 (0.84) HAO1GLATDP1MAPTALDH1A1
SCHEMBL3439644 0.90 HAO1 (0.84) HAO1GLATDP1MAPTALDH1A1
Dimethylamine SCHEMBL14875132 0.88 HAO1 (0.75) HAO1GLATDP1MAPTALDH1A1
SCHEMBL10348520 0.84 HAO1 (0.75) HAO1GLATDP1MAPTALDH1A1
SCHEMBL243735 0.84 HAO1 (0.75) HAO1GLATDP1MAPTALDH1A1
SCHEMBL7067334 0.84 HAO1 (0.75) HAO1GLATDP1MAPTALDH1A1
SCHEMBL11682651 0.83 ALDH1A1 (0.73) HAO1GLATDP1MAPTALDH1A1
SCHEMBL1646481 0.83 AKR1B1 (0.81) CYP2D6CYP2C9F3MAOBAKR1B10
SCHEMBL11682645 0.83 ALDH1A1 (0.73) HAO1GLATDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0817615-B1 PERORAL COMPOSITION FOR CONTROLLED RELEASE IN THE LOWER GASTROINTESTINAL TRACT ORION YHTYMAE OY (FI) 2002-08-07 — — EP claimed
US-5962024-A DRUG RELEASE CONTROLLING AGENT CONSISTS SUBSTANTIALLY OF A PH-SENSITIVE ENTERIC POLYMER. ORION-YHTYMA OY (FI) 1999-10-05 — — US claimed
EP-0239105-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING 5-PHENYL-1,3-DIOXOALKENYL COMPOUNDS G.D. Searle & Co. (US) 1990-05-23 — — EP claimed
EP-0239105-A2 Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl compounds G.D. Searle & Co. (US) 1987-09-30 — — EP claimed
US-4649157-A ANTIALLERGENS, ANTIINFLAMMATORY G. D. SEARLE & CO. (US) 1987-03-10 — — US claimed
CN-118851662-A Sound-absorbing noise-reducing formaldehyde-removing wall material, sound-absorbing noise-reducing formaldehyde-removing wall and preparation method thereof 北京生态家园科技集团有限公司 2024-10-29 — — CN disclosed
US-11939691-B2 Tin or tin alloy electroplating bath, and electronic component having electrodeposit formed thereon using the plating bath ISHIHARA CHEMICAL CO., LTD. (JP) 2024-03-26 — — US disclosed
WO-2022249500-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE 石原ケミカル株式会社 2022-12-01 — — WO disclosed
US-10062657-B2 Method for manufacturing alloy bump ISHIHARA CHEMICAL CO., LTD. (JP) 2018-08-28 — — US disclosed
US-20180207080-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS MERCK PATENT GMBH (DE) 2018-07-26 — — US disclosed
EP-3322400-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS Merck Patent GmbH (DE) 2018-05-23 — — EP disclosed
US-20170330850-A1 METHOD FOR MANUFACTURING ALLOY BUMP ISHIHARA CHEMICAL CO., LTD. (JP) 2017-11-16 — — US disclosed
US-3959292-A HYPOTENSIVE AGENTS, CORONARY DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 — — US disclosed
US-3951994-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 — — US disclosed
US-3951988-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 — — US disclosed
US-3948923-A HYPOTENSIVE, VASODILATION BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 — — US disclosed
US-3946026-A HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 — — US disclosed
US-3939171-A HYPOTENSIVE, VASODILATION BAYER AKTIENGESELLSCHAFT (DT) 1976-02-17 — — US disclosed
US-3935223-A 2-Amino-1,4-dihydropyridine derivatives BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 — — US disclosed
US-3935220-A VASODILATION, HYPOTENSIVE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180207080-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS LPO, CAT, GPX4 HAO1 1451/4885GLA 269/4885TDP1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.