Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 17/20 | 0.90 |
| ▸ | AGTR1 | P30556 | 16/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pratosartan SCHEMBL29657512 | 0.86 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL93596 | 0.84 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL9077584 | 0.80 | AGTR1 (0.76) | AGTR2AGTR1 | |
| SCHEMBL29392553 | 0.76 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL20257334 | 0.74 | AGTR1 (0.89) | AGTR2AGTR1 | |
| SCHEMBL29394346 | 0.74 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL29394324 | 0.74 | AGTR1 (0.89) | AGTR2AGTR1 | |
| Olmesartan SCHEMBL677160 | 0.74 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL23861274 | 0.73 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL13449213 | 0.73 | GP6 (0.78) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |