SCHEMBL1653017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10040646	0.91	FAAH (0.43)	GPR119FAAHLMNAHTTKDM4E
	SCHEMBL10040536	0.91	SPR (0.45)	FAAHLMNAKDM4ESMN1; SMN2NPC1
	Hydrochloric Acid SCHEMBL1653033	0.90	SPR (0.45)	FAAHLMNAKDM4ESMN1; SMN2NPC1
	SCHEMBL10040645	0.89	FAAH (0.40)	FAAHHPGDHSD17B10TSHRALDH1A1
	SCHEMBL10040650	0.88	HDAC1 (0.40)	GPR119FAAHSMN1; SMN2MEN1KMT2A
	SCHEMBL10040647	0.83	SMO (0.40)	GPR119FAAHLMNAHTTKDM4E
	SCHEMBL10040555	0.83	LMNA (0.55)	LMNAHTTSMN1; SMN2TSHRALDH1A1
	SCHEMBL1652158	0.83	GPR119 (0.45)	GPR119FAAHLMNATP53NPC1
	SCHEMBL10040552	0.82	MAPT (0.53)	GPR119FAAHTP53MAPTKMT2A
	SCHEMBL10040562	0.80	SMN1; SMN2 (0.46)	GPR119FAAHLMNAHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.