Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5959955 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL28165008 | 0.95 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL4274364 | 0.95 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL15313172 | 0.95 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL29152718 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL8735136 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Diphenylether SCHEMBL27720609 | 0.88 | TSHR (0.52) | ALDH1A1TSHRTDP1CA2CA9 | |
| Styrene SCHEMBL28479724 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL2119541 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1CYP2A6HDAC8 | |
| Styrene SCHEMBL27724327 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1CYP2A6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065009-A1 | METHOD FOR PHYSICALLY ENCAPSULATING, IN HYDROGEL PARTICLE, LIPOSOME CONTAINING ACTIVE INGREDIENT, AND COSMETIC COMPOSITION CONTAINING SAME | 화코스텍 주식회사 | 2015-05-07 | — | — | WO | claimed |
| US-6528006-B1 | Method of machining preformed plastic film by separation and/or ablation | ADIAM LIFE SCIENCE AG (DE) | 2003-03-04 | — | — | US | claimed |
| EP-0548741-A2 | Chain extended low molecular weight polyoxirane salt complexes for electrostatic applications | THE B.F. GOODRICH COMPANY (US) | 1993-06-30 | — | — | EP | claimed |
| EP-0106530-B1 | DRILLING FLUIDS BASED ON POWDERED SULFONATED THERMOPLASTIC POLYMERS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-09-10 | — | — | EP | claimed |
| EP-0106530-A1 | Drilling fluids based on powdered sulfonated thermoplastic polymers | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-04-25 | — | — | EP | claimed |
| EP-3865873-B1 | METHOD AND ASSAY REAGENT FOR IMMUNOASSAY OF LEUCINE-RICH ALPHA2 GLYCOPROTEIN | SEKISUI MEDICAL CO LTD (JP) | 2024-09-11 | — | — | EP | disclosed |
| US-20240204193-A1 | BINDER COMPOSITION FOR NEGATIVE ELECTRODE AND APPLICATIONS THEREOF | ARKEMA INC. | 2024-06-20 | — | — | US | disclosed |
| CN-117777361-A | Core-shell hydroxyl acrylic wood lacquer emulsion, preparation method thereof and wood lacquer | 无锡洪汇新材料科技股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-4338220-A1 | BINDER COMPOSITION FOR NEGATIVE ELECTRODE AND APPLICATIONS THEREOF | Arkema, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-117652048-A | Binder composition for negative electrode and application thereof | 阿科玛股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-114479779-B | Plugging agent for drilling fluid and preparation method thereof | 中国石油化工股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022241067-A1 | BINDER COMPOSITION FOR NEGATIVE ELECTRODE AND APPLICATIONS THEREOF | ARKEMA INC. (US) | 2022-11-17 | — | — | WO | disclosed |
| US-5132159-A | Paper coating, paints, thermal recording | MITSUI CHEMICALS, INC. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5032455-A | Silyated addition polymers with pendant ionic moieties | PPG INDUSTRIES, INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-4983699-A | Silylated addition polymers with pendant ionic moieties | PPG INDUSTRIES, INC. (US) | 1991-01-08 | — | — | US | disclosed |
| US-4948772-A | HIGH SPEED PRINTING; HIDING POWER | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0377188-A2 | Silylated addition polymers with pendant ionic moieties | PPG INDUSTRIES, INC. (US) | 1990-07-11 | — | — | EP | disclosed |
| EP-0349319-A2 | Substantially flat surfaced vinyl polymer emulsion particles having a concavity and a process for preparing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-01-03 | — | — | EP | disclosed |
| EP-0144116-B1 | DRAG REDUCTION AGENTS FOR AQUEOUS SALT SOLUTIONS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0267597-A2 | Calcium phosphonate scale inhibition | THE B.F. GOODRICH COMPANY (US) | 1988-05-18 | — | — | EP | disclosed |