Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978485 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2ELANECYP1A2SLC6A2SLC6A4 | |
| SCHEMBL3499943 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2ELANECYP1A2SLC6A2SLC6A4 | |
| SCHEMBL27692446 | 0.78 | MAPT (0.42) | GPR35SMN1; SMN2TSHRCYP1A2MAPT | |
| SCHEMBL7982064 | 0.78 | KDM4E (0.39) | SMN1; SMN2ELANEMAPTKMT2AALDH1A1 | |
| SCHEMBL29157410 | 0.78 | KDM4E (0.33) | SCN4ATSHRELANECYP1A2CYP3A4 | |
| SCHEMBL3206927 | 0.74 | GPR35 (0.55) | GPR35TSHRCYP1A2MAPTKMT2A | |
| SCHEMBL48359 | 0.74 | GPR35 (0.55) | GPR35TSHRCYP1A2MAPTKMT2A | |
| SCHEMBL12869701 | 0.73 | ALDH1A1 (0.45) | TSHRELANEKMT2AALDH1A1HTT | |
| SCHEMBL11336164 | 0.73 | MAPT (0.41) | SMN1; SMN2ELANECYP1A2SLC6A2SLC6A4 | |
| SCHEMBL3499945 | 0.73 | CYP1A2 (0.46) | SMN1; SMN2CYP1A2CYP2D6MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | INFLUMEDIX INC. (US) | 2011-04-21 | — | — | US | claimed |
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | INFLUMEDIX INC. (US) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | NEU1, DAO, NEU3 | GPR35 1726/4885SMN1; SMN2 4685/4885SCN4A 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.