Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991472 | 0.92 | P2RX7 (0.41) | P2RX7TP53LMNAGAAPTGES | |
| SCHEMBL16552229 | 0.91 | ALDH1A1 (0.39) | P2RX7LMNAGAAALDH1A1PTGES | |
| SCHEMBL16552200 | 0.91 | P2RX7 (0.39) | P2RX7TP53LMNAGAAIDO1 | |
| SCHEMBL16665036 | 0.90 | TP53 (0.45) | P2RX7TP53LMNAGAAULK1 | |
| SCHEMBL19189934 | 0.90 | HCRTR1 (0.41) | P2RX7TP53LMNAGAAPTGES | |
| SCHEMBL16665046 | 0.89 | LMNA (0.41) | P2RX7LMNAGAAULK1PTGES | |
| SCHEMBL17917771 | 0.89 | P2RX7 (0.43) | P2RX7ALDH1A1PTGESHCRTR1HCRTR2 | |
| SCHEMBL17917773 | 0.88 | P2RX7 (0.43) | P2RX7LMNAGAAALDH1A1 | |
| SCHEMBL17917768 | 0.87 | P2RX7 (0.39) | P2RX7TP53LMNAGAAPTGES | |
| SCHEMBL18503591 | 0.87 | TP53 (0.40) | P2RX7TP53LMNAGAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| EP-3039018-B1 | PYRIDYL CARBOXAMIDE DERIVATIVES WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| WO-2015028427-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | ACHE, DDT, CAT | P2RX7 1029/4885TP53 4859/4885LMNA 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.