Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 12/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552229 | 0.90 | ALDH1A1 (0.39) | HCRTR1HCRTR2PTGESP2RX7LMNA | |
| SCHEMBL16552192 | 0.90 | P2RX7 (0.39) | HCRTR1HCRTR2PTGESTP53P2RX7 | |
| SCHEMBL16665046 | 0.88 | LMNA (0.41) | PTGESP2RX7LMNAGAAKCNK3 | |
| SCHEMBL17917771 | 0.88 | P2RX7 (0.43) | HCRTR1HCRTR2PTGESP2RX7POLB | |
| SCHEMBL17917773 | 0.87 | P2RX7 (0.43) | P2RX7LMNAGAA | |
| SCHEMBL16654673 | 0.86 | P2RX7 (0.44) | P2RX7LMNAGAA | |
| SCHEMBL16665062 | 0.86 | P2RX7 (0.40) | PTGESP2RX7LMNAGAAPOLB | |
| SCHEMBL16665057 | 0.86 | SCN9A (0.40) | PTGESTP53P2RX7 | |
| SCHEMBL17991472 | 0.85 | P2RX7 (0.41) | PTGESTP53P2RX7LMNAGAA | |
| SCHEMBL16552193 | 0.85 | DGAT1 (0.41) | PTGESTP53P2RX7LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039018-B1 | PYRIDYL CARBOXAMIDE DERIVATIVES WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |