SCHEMBL16552330

SCHEMBL16552330

CNc1ccc(-c2c3nc(c(-c4ccccc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.54
▸ CYCS P99999 4/20 0.52
▸ TERT O14746 4/20 0.51
▸ STAT3 P40763 1/20 0.50
▸ STAT1 P42224 1/20 0.50
▸ ABCG2 Q9UNQ0 1/20 0.48
▸ ENPP2 Q13822 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6394334 0.94 TERT (0.57) TOP1CYCSTERTABCG2ENPP2
SCHEMBL16923752 0.91 TOP1 (0.46) TOP1CYCSTERTSTAT3STAT1
SCHEMBL16923754 0.91 TOP1 (0.46) TOP1CYCSTERTSTAT3STAT1
Dimethylamine SCHEMBL21174852 0.89 TERT (0.58) TOP1CYCSTERTSTAT3STAT1
SCHEMBL16552258 0.89 TOP1 (0.44) TOP1CYCSTERTSTAT3STAT1
SCHEMBL29405434 0.85 TOP1 (0.64) TOP1CYCSTERTSTAT3STAT1
SCHEMBL30136 0.85 TOP1 (0.64) TOP1CYCSTERTSTAT3STAT1
SCHEMBL27674814 0.85 TOP1 (0.54) TOP1CYCSTERTSTAT3STAT1
SCHEMBL5013660 0.84 TOP1 (0.56) TOP1CYCSTERTSTAT3STAT1
SCHEMBL16920363 0.84 TOP1 (0.50) TOP1CYCSTERTSTAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185901-B1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2023-10-04 — — EP disclosed
EP-2849791-B1 CONJUGATE OF A PHOTOSENSITISER AND CHITOSAN AND USES THEREOF PCI BIOTECH AS (NO) 2018-07-04 — — EP disclosed
US-20170252441-A1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2017-09-07 — — US disclosed
US-20160206725-A1 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION PCI BIOTECH AS (NO) 2016-07-21 — — US disclosed
WO-2016030529-A1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2016-03-03 — — WO disclosed
WO-2016030528-A1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2016-03-03 — — WO disclosed
US-20150202293-A1 CONJUGATE OF A PHOTOSENSITISER AND CHITOSAN AND USES THEREOF PCI BIOTECH AS (NO) 2015-07-23 — — US disclosed
WO-2015028574-A1 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION PCI BIOTECH AS (NO) 2015-03-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150202293-A1 CONJUGATE OF A PHOTOSENSITISER AND CHITOSAN AND USES THEREOF TLR3, CD47, TLR9 TOP1 2741/4885CYCS 3103/4885TERT 2440/4885
US-20170252441-A1 COMPOUND AND METHOD CSF3R, IL2, IL5 TOP1 2013/4885CYCS 2836/4885TERT 3202/4885
US-20160206725-A1 COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION TLR9, TLR3, TLR1 TOP1 3662/4885CYCS 4582/4885TERT 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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