Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.56 |
| ▸ | CYCS | P99999 | 3/20 | 0.55 |
| ▸ | TERT | O14746 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013009 | 0.86 | STAT3 (0.49) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL5134837 | 0.85 | STAT3 (0.48) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL27674814 | 0.84 | TOP1 (0.54) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL16552330 | 0.84 | TOP1 (0.54) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL30136 | 0.84 | TOP1 (0.64) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL29405434 | 0.84 | TOP1 (0.64) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL5013925 | 0.83 | STAT3 (0.71) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL15085674 | 0.83 | TOP1 (0.62) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL991489 | 0.83 | TOP1 (0.62) | TOP1CYCSTERTENPP2STAT3 | |
| SCHEMBL7987113 | 0.83 | TOP1 (0.62) | TOP1CYCSTERTENPP2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417142-B2 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-02-09 | — | — | US | disclosed |
| US-6951935-B2 | Heteroatom-substituted porphyrins and methods for synthesis of same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2005-10-04 | — | — | US | disclosed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | disclosed |
| US-20030236400-A1 | Heteroatom-substituted porphyrins and methods for synthesis of same | UNIVERSITY OF TENNESSEE RESEARCH CORPORATION | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | PPOX, HCCS, ICOSLG | TOP1 1268/4885CYCS 6/4885TERT 645/4885 |
| US-20030236400-A1 | Heteroatom-substituted porphyrins and methods for synthesis of same | PPOX, HMBS, UROD | TOP1 3026/4885CYCS 19/4885TERT 2629/4885 |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | PPOX, PPIF, HMBS | TOP1 1564/4885CYCS 57/4885TERT 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.