Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.57 |
| ▸ | TOP1 | P11387 | 4/20 | 0.55 |
| ▸ | CYCS | P99999 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552330 | 0.94 | TOP1 (0.54) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL16923754 | 0.85 | TOP1 (0.46) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL16923752 | 0.85 | TOP1 (0.46) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL16552258 | 0.83 | TOP1 (0.44) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL38662506 | 0.83 | TOP1 (0.56) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL6394821 | 0.81 | TERT (0.49) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL29693624 | 0.80 | TERT (0.62) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL5013660 | 0.80 | TOP1 (0.56) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL8994447 | 0.80 | TOP1 (0.60) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL31040346 | 0.79 | TERT (0.60) | TERTTOP1CYCSENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130189347-A1 | DISEASE TREATMENT DRUG | YUASA MAKOTO (JP) | 2013-07-25 | — | — | US | disclosed |
| EP-2601954-A1 | THERAPEUTIC AGENT FOR DISEASE | Yuasa, Makoto (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-20050008687-A1 | Metal-porphyrin-complex-embedded liposomes, production process thereof, and medicines making use of the same | MAKOTO YUASA (JP) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130189347-A1 | DISEASE TREATMENT DRUG | PPOX, TFRC, SLC40A1 | TERT 3039/4885TOP1 3561/4885CYCS 1544/4885 |
| US-20050008687-A1 | Metal-porphyrin-complex-embedded liposomes, production process thereof, and medicines making use of the same | GPX4, FECH, PPOX | TERT 2685/4885TOP1 3088/4885CYCS 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.