SCHEMBL16553523

SCHEMBL16553523

O=CCOc1cc(I)cc(I)c1I

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ERN1 O75460 1/20 0.33
▸ CTSL P07711 1/20 0.32
▸ CTSS P25774 1/20 0.32
▸ CTSK P43235 1/20 0.32
▸ TUBB1 Q9H4B7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16553559 0.78 ERN1 (0.36) ERN1TUBB1
SCHEMBL28093668 0.74 ERN1 (0.36) ERN1
SCHEMBL17861606 0.69 TUBB1 (0.38) CTSSCTSKTUBB1
SCHEMBL26586914 0.69 — —
SCHEMBL14407366 0.67 L3MBTL1 (0.34) —
SCHEMBL24933380 0.63 APP (0.50) —
SCHEMBL14291570 0.61 APP (0.39) —
SCHEMBL29425553 0.61 ERN1 (0.61) ERN1
SCHEMBL6900249 0.61 ERN1 (0.61) ERN1
Formaldehyde SCHEMBL28061059 0.61 TTR (0.45) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11957755-B2 Radiopaque polymers Boston Scientific Medical Device Limited (IE) 2024-04-16 — — US disclosed
US-20230355833-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LIMITED (GB) 2023-11-09 — — US disclosed
CN-111518285-B Imageable polymers 生物兼容英国有限公司 2023-09-22 — — CN disclosed
US-11744916-B2 Radiopaque polymers BIOCOMPATIBLES UK LIMITED 2023-09-05 — — US disclosed
EP-3492110-B1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2023-03-08 — — EP disclosed
CN-110950981-B Radiopaque polymers 生物兼容英国有限公司 2023-02-17 — — CN disclosed
CN-111494699-B Radiopaque polymers 生物兼容英国有限公司 2022-05-31 — — CN disclosed
EP-3999559-A1 RADIOPAQUE POLYMERS Biocompatibles UK Limited (GB) 2022-05-25 — — EP disclosed
EP-4000639-A1 IMAGEABLE POLYMERS Biocompatibles Uk Ltd. (GB) 2022-05-25 — — EP disclosed
CN-114127134-A Radiopaque polymers 生物相容英国有限公司 2022-03-01 — — CN disclosed
US-10098972-B2 Imageable polymers BIOCOMPATIBLES UK LTD. (GB) 2018-10-16 — — US disclosed
US-9895452-B2 Imageable polymers BIOCOMPATIBLES UK LIMITED (GB) 2018-02-20 — — US disclosed
US-20160228556-A1 Radiopaque Polymers Boston Scientific Medical Device Limited (IE) 2016-08-11 — — US disclosed
EP-3041515-A1 RADIOPAQUE POLYMERS Biocompatibles Uk Ltd. (GB) 2016-07-13 — — EP disclosed
EP-3041516-A1 IMAGEABLE POLYMERS Biocompatibles Uk Ltd. (GB) 2016-07-13 — — EP disclosed
US-20160193367-A1 Imageable Polymers BIOCOMPATIBLES UK LTD (GB) 2016-07-07 — — US disclosed
WO-2015033093-A9 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2016-04-07 — — WO disclosed
US-20150110722-A1 IMAGEABLE POLYMERS Boston Scientific Medical Device Limited (IE) 2015-04-23 — — US disclosed
WO-2015033093-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2015-03-12 — — WO disclosed
WO-2015033092-A1 IMAGEABLE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2015-03-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160228556-A1 Radiopaque Polymers RAD51, RXFP3, RXFP1 ERN1 3995/4885CTSL 4192/4885CTSS 3171/4885
US-10098972-B2 Imageable polymers VHL, FLT4, FLT1 ERN1 1786/4885CTSL 3024/4885CTSS 3716/4885
US-20150110722-A1 IMAGEABLE POLYMERS BRDT, BRD3, BRD2 ERN1 3538/4885CTSL 4297/4885CTSS 2729/4885
US-20230355833-A1 RADIOPAQUE POLYMERS TPO, PGLS, IQGAP1 ERN1 3496/4885CTSL 2742/4885CTSS 4209/4885
US-11957755-B2 Radiopaque polymers RXFP3, RXFP1, DAGLA ERN1 3490/4885CTSL 4459/4885CTSS 4277/4885
US-20160193367-A1 Imageable Polymers VHL, FLT4, FLT1 ERN1 1786/4885CTSL 3024/4885CTSS 3716/4885
US-11744916-B2 Radiopaque polymers TPO, PGLS, IQGAP1 ERN1 3496/4885CTSL 2742/4885CTSS 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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