Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amiloxate SCHEMBL26646558 | 0.93 | ALDH1A1 (0.64) | LMNAALDH1A1MAPK1TDP1MEN1 | |
| Octocrylene SCHEMBL28166919 | 0.93 | LMNA (0.64) | LMNAALDH1A1MAPK1TDP1MEN1 | |
| Amiloxate SCHEMBL26646557 | 0.93 | ALDH1A1 (0.64) | LMNAALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL469376 | 0.89 | ALDH1A1 (0.86) | LMNAALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL21908164 | 0.89 | ALDH1A1 (0.86) | LMNAALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL16762811 | 0.89 | ALDH1A1 (0.86) | LMNAALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL346933 | 0.89 | ALDH1A1 (0.86) | LMNAALDH1A1MAPK1TDP1CYP3A4 | |
| Octinoxate SCHEMBL1408448 | 0.86 | TDP1 (0.84) | LMNAALDH1A1MAPK1TDP1MEN1 | |
| Octocrylene SCHEMBL1769135 | 0.84 | ALDH1A1 (1.00) | LMNAALDH1A1MAPK1TDP1MEN1 | |
| Octocrylene SCHEMBL16483 | 0.84 | ALDH1A1 (1.00) | LMNAALDH1A1MAPK1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202735-A1 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | TPC-API LLC | 2022-06-30 | — | — | US | disclosed |
| EP-3345594-B1 | SOLUBILIZED FLAVONOID COMPOSITION | TECH INVESTMENTS LC (US) | 2021-11-17 | — | — | EP | disclosed |
| US-11135177-B2 | Methods of making and using compositions comprising flavonoids | VIZURI HEALTH SCIENCES CONSUMER HEALTHCARE, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| US-20210000958-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | VIZURI HEALTH SCIENCES CONSUMER HEALTHCARE, INC. | 2021-01-07 | — | — | US | disclosed |
| EP-3345594-A1 | SOLUBILIZED FLAVONOID COMPOSITION | Vizuri Health Sciences LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| US-9889098-B2 | Methods of making and using compositions comprising flavonoids | VIZURI HEALTH SCIENCES LLC (US) | 2018-02-13 | — | — | US | disclosed |
| US-20180008553-A1 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | TPC-API LLC | 2018-01-11 | — | — | US | disclosed |
| EP-2629763-B1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUNDS | VIZURI HEALTH SCIENCES LLC (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20170296668-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | VIZURI HEALTH SCIENCES CONSUMER HEALTHCARE, INC. | 2017-10-19 | — | — | US | disclosed |
| US-9730953-B2 | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compound | VIZURI HEALTH SCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2701670-A1 | CLEAR WET SPRAYS AND GELS | Isp Investments Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| US-8637569-B2 | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds | API GENESIS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| EP-2629763-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUNDS | API Genesis, LLC (US) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012149355-A1 | CLEAR WET SPRAYS AND GELS | ISP INVESTMENTS INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-2490679-A2 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | API Genesis, LLC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20120213842-A1 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | TPC-API LLC | 2012-08-23 | — | — | US | disclosed |
| WO-2012078961-A1 | COMPOSITIONS COMPRISING STABILIZED KETO-ENOL UV ABSORBERS | ISP INVESTMENT INS. (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2011049629-A9 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | API GENESIS, LLC (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012054090-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUNDS | API GENESIS, LLC (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2011049629-A2 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | API GENESIS, LLC (US) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135177-B2 | Methods of making and using compositions comprising flavonoids | F3, C5, CYP51A1 | LMNA 2475/4885ALDH1A1 2963/4885MAPK1 2120/4885 |
| US-20220202735-A1 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | F3, C5, CYP51A1 | LMNA 2475/4885ALDH1A1 2963/4885MAPK1 2120/4885 |
| US-20210000958-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | ABCG2, CYP2F1, LSS | LMNA 3422/4885ALDH1A1 1920/4885MAPK1 2589/4885 |
| US-20180008553-A1 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | F3, C5, CYP51A1 | LMNA 2475/4885ALDH1A1 2963/4885MAPK1 2120/4885 |
| US-20170296668-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | ABCG2, CYP2F1, LSS | LMNA 3422/4885ALDH1A1 1920/4885MAPK1 2589/4885 |
| US-20120213842-A1 | METHODS OF MAKING AND USING COMPOSITIONS COMPRISING FLAVONOIDS | F3, C5, CYP51A1 | LMNA 2475/4885ALDH1A1 2963/4885MAPK1 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.