Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | PRKACG | P22612 | 1/20 | 0.30 |
| ▸ | PRKACB | P22694 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653870 | 0.87 | ACLY (0.36) | ALPLKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11913446 | 0.83 | SGK1 (0.30) | KIT | |
| SCHEMBL11903262 | 0.82 | LIMK1 (0.31) | ALPLKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11903110 | 0.80 | ROCK2 (0.31) | ALPLKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10252352 | 0.79 | KDM4E (0.35) | ALPLKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11913421 | 0.78 | HSD17B10 (0.36) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11902934 | 0.78 | TRPV1 (0.39) | KDM4EALDH1A1HSD17B10PKMRHEB | |
| SCHEMBL116281 | 0.78 | KDM4E (0.36) | ALPLKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL721102 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1PKMRCE1MAP4K1 | |
| SCHEMBL119041 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1PKMRCE1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488518-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| CN-102574849-A | Herbicidal compounds | SYNGENTA LTD | 2012-07-11 | — | — | CN | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | ALPL 1784/4885KDM4E 3599/4885ALDH1A1 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.