SCHEMBL16555277

SCHEMBL16555277

Nc1nc2c(ncn2[C@@H]2O[C@H](C(O)(F)F)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HINT1 P49773 4/20 0.55
▸ NT5E P21589 1/20 0.55
▸ STING1 Q86WV6 3/20 0.55
▸ PDE3B Q13370 1/20 0.55
▸ PDE3A Q14432 1/20 0.55
▸ GSK3A P49840 2/20 0.52
▸ RPS6KA3 P51812 2/20 0.52
▸ MAPK14 Q16539 2/20 0.52
▸ PNP P00491 1/20 0.52
▸ TGM2 P21980 1/20 0.51
▸ TAAR1 Q96RJ0 1/20 0.51
▸ KRAS P01116 2/20 0.51
▸ HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237754 0.84 HINT1 (0.58) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL8199215 0.82 HINT1 (0.53) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL2510562 0.82 HINT1 (0.62) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL4278130 0.82 HINT1 (0.62) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL19938159 0.82 HINT1 (0.62) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL24299397 0.82 HINT1 (0.62) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL11183383 0.82 HINT1 (0.59) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL13833323 0.82 HINT1 (0.62) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL16114092 0.82 HINT1 (0.62) HINT1NT5ESTING1PDE3BPDE3A
SCHEMBL1120568 0.81 HINT1 (0.59) HINT1NT5ESTING1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096203-A1 TARGETING A CHIMERIC RNA FOR TREATING CANCER UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-05-08 — — WO disclosed
WO-2024035952-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES REMIX THERAPEUTICS INC. (US) 2024-02-15 — — WO disclosed
CN-114404581-A Cancer vaccine 摩登纳特斯有限公司 2022-04-29 — — CN disclosed
EP-3169335-A2 CIRCULAR POLYNUCLEOTIDES Moderna Therapeutics, Inc. (US) 2017-05-24 — — EP disclosed
EP-3041934-A1 CHIMERIC POLYNUCLEOTIDES Moderna Therapeutics, Inc. (US) 2016-07-13 — — EP disclosed
WO-2016011222-A2 CIRCULAR POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2016-01-21 — — WO disclosed
WO-2015034928-A1 CHIMERIC POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2015-03-12 — — WO disclosed
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