Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.82 |
| ▸ | HPGD | P15428 | 4/20 | 0.82 |
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.82 |
| ▸ | GAA | P10253 | 2/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | CFTR | P13569 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809277 | 0.91 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL30041521 | 0.91 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL4604088 | 0.87 | ALDH1A1 (0.85) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL165608 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL221403 | 0.81 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL29481401 | 0.80 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL1015993 | 0.80 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL14081421 | 0.80 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL29543806 | 0.79 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL26466965 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065671-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS | MERCK SHARP & DOHME CORP. | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065671-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS | GPR119, GPR39, GPR65 | ALDH1A1 833/4885KDM4E 3477/4885HPGD 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.