Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.41 |
| ▸ | PIM1 | P11309 | 5/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16563605 | 0.80 | MEN1 (0.45) | ALOX15RAB9A | |
| SCHEMBL16564046 | 0.78 | P2RX7 (0.47) | ALOX15ROCK2RAB9A | |
| SCHEMBL16563497 | 0.77 | PTGES (0.39) | ALOX15JAK2RAB9A | |
| SCHEMBL16563847 | 0.77 | MEN1 (0.47) | RAB9A | |
| SCHEMBL16564040 | 0.77 | ORAI1 (0.52) | ALOX15ROCK2RAB9AMAPK7 | |
| SCHEMBL16564132 | 0.77 | KMT2A (0.44) | ALOX15RAB9A | |
| SCHEMBL16563900 | 0.76 | MAPT (0.50) | — | |
| SCHEMBL16563773 | 0.76 | MAPT (0.43) | JAK2JAK1TYK2RAB9A | |
| SCHEMBL1706179 | 0.76 | TYK2 (0.59) | JAK2JAK1TYK2ROCK2MCL1 | |
| SCHEMBL16563623 | 0.76 | ALOX15 (0.42) | ALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848615-A1 | New pyrazole derivatives as CRAC channel modulators | Almirall, S.A. (ES) | 2015-03-18 | — | — | EP | claimed |
| EP-2848615-A1 | New pyrazole derivatives as CRAC channel modulators | Almirall, S.A. (ES) | 2015-03-18 | — | — | EP | disclosed |