Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019777 | 0.82 | KDM1A (0.33) | KDM1AMAOB | |
| SCHEMBL16579959 | 0.80 | GNAI3 (0.35) | KDM1AMAOB | |
| SCHEMBL14768884 | 0.79 | PIM1 (0.31) | PIM1FLT3PIM3PIM2 | |
| SCHEMBL255863 | 0.78 | SIGMAR1 (0.32) | — | |
| SCHEMBL14297527 | 0.76 | TSHR (0.33) | KDM1AMAOBKDM4E | |
| SCHEMBL22704494 | 0.75 | CARM1 (0.31) | KDM4E | |
| SCHEMBL18633184 | 0.73 | L3MBTL1 (0.31) | KDM1A | |
| SCHEMBL22704373 | 0.73 | KDM4E (0.34) | KDM4E | |
| SCHEMBL15653919 | 0.73 | EPHX1 (0.39) | KDM1AMAOBKDM4EKMT2A | |
| SCHEMBL904100 | 0.73 | APLNR (0.44) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023018237-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2015038426-A1 | SELF-IMMOLATIVE LINKERS CONTAINING MANDELIC ACID DERIVATIVES, DRUG-LIGAND CONJUGATES FOR TARGETED THERAPIES AND USES THEREOF | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |