Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24294685 | 0.85 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL16579986 | 0.78 | KDM1A (0.32) | — | |
| SCHEMBL26707596 | 0.78 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL22704494 | 0.78 | CARM1 (0.31) | — | |
| SCHEMBL18633184 | 0.77 | L3MBTL1 (0.31) | — | |
| SCHEMBL22704373 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL24511399 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL18862773 | 0.73 | — | — | |
| SCHEMBL8266096 | 0.73 | CTSL (0.33) | SIGMAR1 | |
| SCHEMBL19195126 | 0.73 | HTR2A (0.31) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027960-A1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | 山东轩竹医药科技有限公司 (CN) | 2012-03-08 | — | — | WO | disclosed |