Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20246785 | 0.78 | ALDH1A1 (0.55) | HSD17B10KMT2AHPGDNPC1MAPT | |
| SCHEMBL9686607 | 0.78 | KMT2A (0.49) | TDP1HSD17B10THRBKMT2AHPGD | |
| SCHEMBL90967 | 0.77 | ALDH1A1 (0.59) | TDP1HSD17B10KMT2AHPGDNPC1 | |
| SCHEMBL12446713 | 0.77 | MAPT (0.44) | THRBKMT2AHPGDNPC1MAPT | |
| SCHEMBL1224549 | 0.76 | KCNMA1 (0.62) | THRBKMT2ANPC1MAPTHTT | |
| SCHEMBL22791425 | 0.75 | GAA (0.37) | HPGDNPC1MAPTHTTGAA | |
| SCHEMBL4913081 | 0.74 | RXFP1 (0.51) | TDP1HSD17B10THRBKMT2AHPGD | |
| SCHEMBL10034515 | 0.74 | LMNA (0.56) | TDP1HSD17B10KMT2AHPGDNPC1 | |
| SCHEMBL30832967 | 0.74 | HDAC1 (0.60) | TDP1HSD17B10THRBKMT2AHPGD | |
| SCHEMBL10896720 | 0.74 | ALDH1A1 (0.60) | TDP1HSD17B10KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313435-B2 | BLEACHING COMPOSITION FOR DYED KERATINOUS FIBRES | ORÉAL L (FR) | 2016-08-10 | — | — | EP | disclosed |
| EP-1326576-B2 | COSMETIC COMPOSITION CONTAINING SULPHINIC ACID DERIVATIVES | ORÉAL L (FR) | 2015-03-25 | — | — | EP | disclosed |