Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060991 | 0.85 | HPGD (0.37) | GAARAPGEF4HPGDCYP1A2CYP2A6 | |
| SCHEMBL20860302 | 0.83 | ADRA2A (0.32) | ADRA2AEGFRAPP | |
| SCHEMBL20860303 | 0.79 | SIGMAR1 (0.37) | GAACYP1A2CYP3A4ADRA2ACYP2C9 | |
| SCHEMBL10284425 | 0.78 | GAA (0.41) | GAARAPGEF4HPGDCYP1A2CYP2A6 | |
| SCHEMBL8342155 | 0.78 | GAA (0.37) | GAARAPGEF4HPGDCYP1A2CYP2A6 | |
| SCHEMBL22791511 | 0.78 | CYP3A4 (0.39) | GAARAPGEF4HPGDCYP1A2CYP3A4 | |
| SCHEMBL21374130 | 0.76 | LMNA (0.34) | GAAHPGDCYP1A2CYP3A4NPC1 | |
| SCHEMBL21239424 | 0.75 | CYP3A4 (0.39) | GAARAPGEF4HPGDCYP1A2CYP2A6 | |
| SCHEMBL20726532 | 0.75 | GAA (0.39) | GAARAPGEF4HPGDCYP1A2CYP3A4 | |
| SCHEMBL16588403 | 0.75 | TDP1 (0.50) | GAAHPGDCYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180463-A1 | ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS | Technische Universität Berlin (DE) | 2023-09-28 | — | — | WO | disclosed |
| WO-2020252205-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | Praxis Biotech LLC (US) | 2020-12-17 | — | — | WO | disclosed |