SCHEMBL24334965

SCHEMBL24334965

Cc1cc(C)cc(Cn2ccc3ccc(Cl)nc32)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CYP11B1 P15538 2/20 0.39
▸ CYP11B2 P19099 2/20 0.39
▸ MAPT P10636 5/20 0.38
▸ LMNA P02545 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ BRD4 O60885 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ P2RX7 Q99572 2/20 0.36
▸ TP53 P04637 3/20 0.35
▸ POLB P06746 1/20 0.35
▸ CCR9 P51686 1/20 0.34
▸ HCRTR2 O43614 1/20 0.34
▸ HTR6 P50406 2/20 0.33
▸ NPBWR1 P48145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24334961 0.81 KMT2A (0.48) ALDH1A1KMT2ABRD4L3MBTL1HTR6
SCHEMBL30424558 0.81 KMT2A (0.48) ALDH1A1KMT2ABRD4L3MBTL1HTR6
SCHEMBL16591995 0.78 MAPT (0.45) CYP11B1CYP11B2MAPTALDH1A1HTT
SCHEMBL16794770 0.74 ENPP2 (0.47) MAPTALDH1A1RECQLKMT2AL3MBTL1
SCHEMBL24334963 0.73 P2RX7 (0.37) CYP11B1CYP11B2BRD4P2RX7
SCHEMBL29564933 0.73 P2RX7 (0.37) CYP11B1CYP11B2BRD4P2RX7
SCHEMBL16804387 0.72 YTHDC1 (0.50) CYP11B2ALDH1A1RAB9A
SCHEMBL1513289 0.72 DBH (0.47) LMNAALDH1A1HTTRAB9AKMT2A
SCHEMBL26804233 0.71 EPHX2 (0.34) CYP11B1CYP11B2MAPTLMNAP2RX7
SCHEMBL26804232 0.70 P2RX7 (0.34) CYP11B1CYP11B2P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382929-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-30 — — US disclosed
US-20230382929-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-30 — — US disclosed
CN-116323626-A Olefin polymerization catalyst with 6-amino-N-arylazaindole ligands 陶氏环球技术有限责任公司 2023-06-23 — — CN disclosed
WO-2022081685-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND DOW GLOBAL TECHNOLOGIES LLC (US) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382929-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND AZI2, AOC2, CCNI CYP11B1 2466/4885CYP11B2 2117/4885MAPT 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback