Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261586 | 0.79 | PARP10 (0.39) | PARP10PARP1GRM5PARP11 | |
| SCHEMBL24457969 | 0.76 | PARP10 (0.37) | PARP10PARP1GRM5PARP11 | |
| SCHEMBL6200381 | 0.74 | MEN1 (0.47) | PARP10PARP1GRM5PARP11 | |
| SCHEMBL10300799 | 0.73 | PARP1 (0.35) | PARP10PARP1GRM5 | |
| SCHEMBL29285141 | 0.72 | ERN1 (0.39) | PARP10PARP1GRM5PARP11 | |
| SCHEMBL14159974 | 0.69 | LMNA (0.46) | — | |
| SCHEMBL19711548 | 0.69 | PNMT (0.44) | PARP1 | |
| SCHEMBL6200236 | 0.68 | PARP10 (0.45) | PARP10PARP1GRM5PARP11 | |
| SCHEMBL2361634 | 0.68 | PARP1 (0.33) | PARP10PARP1 | |
| SCHEMBL22932415 | 0.67 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579438-B | Compounds and methods for skin repair | 阿勒根公司 | 2019-12-06 | — | — | CN | disclosed |
| US-9546162-B2 | Compounds and methods for skin repair | ALLERGAN, INC. (US) | 2017-01-17 | — | — | US | disclosed |
| US-9546162-B2 | Compounds and methods for skin repair | ALLERGAN, INC. (US) | 2017-01-17 | — | — | US | disclosed |
| US-9546162-B2 | Compounds and methods for skin repair | ALLERGAN, INC. (US) | 2017-01-17 | — | — | US | disclosed |
| EP-3049392-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2016-08-03 | — | — | EP | disclosed |
| CN-105579438-A | Compounds and methods for skin repair | ALLERGAN INC | 2016-05-11 | — | — | CN | disclosed |
| US-20150094330-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN INC (US) | 2015-04-02 | — | — | US | disclosed |
| US-20150094330-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN INC (US) | 2015-04-02 | — | — | US | disclosed |
| US-20150094330-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN INC (US) | 2015-04-02 | — | — | US | disclosed |
| WO-2015048553-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015048553-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | ALLERGAN, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094330-A1 | COMPOUNDS AND METHODS FOR SKIN REPAIR | PTGER4, LTB4R2, LTB4R | PARP10 559/4885PARP1 329/4885GRM5 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.