SCHEMBL8415435

SCHEMBL8415435

C=C(C)C(=O)OCCONc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
TDP1 Q9NUW8 3/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
GAA P10253 3/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
TSHR P16473 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ELANE P08246 1/20 0.39
GPR174 Q9BXC1 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706212 0.83 ALDH1A1 (0.47) SMN1; SMN2GAAALDH1A1TSHRNPSR1
SCHEMBL1087332 0.81 NPC1 (0.60) TDP1SMN1; SMN2ALDH1A1TSHRNPSR1
SCHEMBL305728 0.79 POLB (0.44) THRBTDP1POLBAPEX1HTT
Benzene SCHEMBL28145673 0.79 THRB (0.65) THRBTDP1POLBAPEX1HTT
Toluene SCHEMBL28087905 0.78 THRB (0.52) THRBTDP1POLBAPEX1HTT
Hydrochloric Acid SCHEMBL11047494 0.78 POLB (0.43) THRBTDP1POLBAPEX1HTT
Dimethylamine SCHEMBL1021289 0.78 LMNA (0.56) THRBTDP1POLBAPEX1HTT
SCHEMBL16595000 0.78 TDP1 (0.41) THRBTDP1POLBAPEX1HTT
SCHEMBL27523375 0.77 CYP1A2 (0.56) HTTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL42893 0.77 HCAR2 (0.51) THRBTDP1POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0567083-B1 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO LTD (JP) 1999-09-01 EP disclosed
EP-0576880-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1998-12-23 EP disclosed
US-5405738-A A perfect cubic silver halide grains are spectrally sensitized with sensitizing dyes; photosensitivity, contrast, high color density, image quality FUJI PHOTO FILM CO., LTD. (JP) 1995-04-11 US disclosed
US-5370984-A Containing an addition polymer FUJI PHOTO FILM CO., LTD. (JP) 1994-12-06 US disclosed
EP-0576880-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-01-05 EP disclosed
EP-0567083-A1 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-10-27 EP disclosed