SCHEMBL4455176

SCHEMBL4455176

C=C(C)C(=O)OCCC(C)[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TSHR P16473 3/20 0.38
ELANE P08246 1/20 0.38
THRB P10828 1/20 0.36
MTNR1A P48039 5/20 0.35
MTNR1B P49286 5/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2791519 0.76 TSHR (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL235139 0.76 MTNR1A (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL513073 0.76 TDP1 (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL13559176 0.76 ELANE (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL28081638 0.75 THRB (0.51) TDP1POLBAPEX1HTTTSHR
SCHEMBL16595000 0.75 TDP1 (0.41) TDP1POLBAPEX1HTTTSHR
SCHEMBL230778 0.75 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL8899641 0.75 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL5724911 0.75 HPGD (0.37) TDP1TSHRMTNR1AMTNR1B
SCHEMBL8899918 0.74 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090030093-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS BASF AKTIENGESSELLSCHAFT (DE) 2009-01-29 US disclosed
US-7417098-B2 Method for emulsion polymerisation of olefins BASF SE (DE) 2008-08-26 US disclosed
US-20080182915-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS BASF AKTIENGESELLSCHAFT (DE) 2008-07-31 US disclosed
US-20070043163-A1 Method for emulsion polymerisation of olefins BASF AKTIENGESELLSCHAFT (DE) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182915-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS SQLE, PHOSPHO1, ALOX15 TDP1 3650/4885POLB 86/4885APEX1 832/4885
US-20070043163-A1 Method for emulsion polymerisation of olefins PHOSPHO1, SQLE, ALOX15 TDP1 4032/4885POLB 91/4885APEX1 974/4885
US-20090030093-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS PHOSPHO1, SQLE, ALOX15 TDP1 4032/4885POLB 91/4885APEX1 974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.