Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | FABP1 | P07148 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596171 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL16596197 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL16596174 | 0.98 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL988490 | 0.94 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL29676577 | 0.94 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL29584120 | 0.89 | KDM4E (0.61) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL3095787 | 0.89 | KDM4E (0.61) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL30639265 | 0.89 | PPARA (0.58) | HDAC1HDAC2PPARAFFAR1FABP1 | |
| SCHEMBL2801030 | 0.85 | MAOB (0.60) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL4086003 | 0.83 | CNR2 (0.67) | HDAC1HDAC2PPARAFABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
| WO-2015042363-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | BLVRB, PGLS, GRHPR | ALDH1A1 4735/4885KMT2A 4247/4885MAPT 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.