Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601126 | 0.90 | L3MBTL1 (0.47) | L3MBTL1FAAHACHEHRH3PARP1 | |
| SCHEMBL16601135 | 0.89 | L3MBTL1 (0.46) | L3MBTL1FAAHACHEHRH3PARP1 | |
| SCHEMBL16600776 | 0.86 | L3MBTL1 (0.44) | L3MBTL1FAAHS1PR1S1PR5KDM4E | |
| SCHEMBL16600850 | 0.85 | L3MBTL1 (0.41) | L3MBTL1FAAHACHEHSD11B1HTT | |
| SCHEMBL16600858 | 0.84 | HRH3 (0.39) | L3MBTL1FAAHHRH3PARP1S1PR1 | |
| SCHEMBL16600857 | 0.84 | HRH3 (0.39) | L3MBTL1FAAHHRH3PARP1S1PR1 | |
| SCHEMBL16601212 | 0.83 | FAAH (0.37) | L3MBTL1FAAHPARP1PARP2KDM4E | |
| SCHEMBL16601210 | 0.83 | FAAH (0.37) | L3MBTL1FAAHPARP1PARP2KDM4E | |
| SCHEMBL16600970 | 0.81 | RAB9A (0.45) | FAAHHRH3 | |
| SCHEMBL16600968 | 0.81 | RAB9A (0.45) | FAAHHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | disclosed |