Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600870 | 0.91 | CHRNB2 (0.44) | L3MBTL1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL16600792 | 0.85 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2HSD11B1ACHEALDH1A1 | |
| SCHEMBL16601126 | 0.79 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2NPC1HSD11B1ACHE | |
| SCHEMBL16601135 | 0.78 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2KMT2ALMNAMAPK1 | |
| SCHEMBL9521359 | 0.76 | KMT2A (0.58) | L3MBTL1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL16601212 | 0.76 | FAAH (0.37) | L3MBTL1KMT2ALMNAMEN1TSHR | |
| SCHEMBL16601210 | 0.76 | FAAH (0.37) | L3MBTL1KMT2ALMNAMEN1TSHR | |
| SCHEMBL16601522 | 0.76 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL16601523 | 0.76 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL16600776 | 0.76 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | disclosed |