Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601212 | 1.00 | FAAH (0.37) | FAAHALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL16601135 | 0.89 | L3MBTL1 (0.46) | FAAHALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL16600857 | 0.88 | HRH3 (0.39) | FAAHKMT2AMAPK1L3MBTL1RAB9A | |
| SCHEMBL16600858 | 0.88 | HRH3 (0.39) | FAAHKMT2AMAPK1L3MBTL1RAB9A | |
| SCHEMBL16600970 | 0.85 | RAB9A (0.45) | FAAHKMT2AMAPK1RAB9A | |
| SCHEMBL16600968 | 0.85 | RAB9A (0.45) | FAAHKMT2AMAPK1RAB9A | |
| SCHEMBL16601295 | 0.85 | L3MBTL1 (0.43) | ALDH1A1KDM4EKMT2AMAPK1HPGD | |
| SCHEMBL16600792 | 0.83 | L3MBTL1 (0.46) | FAAHALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL16601074 | 0.81 | CHRNA4 (0.47) | KMT2AMAPK1 | |
| SCHEMBL16601126 | 0.79 | L3MBTL1 (0.47) | FAAHALDH1A1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | claimed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | claimed |