Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 16/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 8/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 8/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601295 | 0.86 | L3MBTL1 (0.43) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL16600968 | 0.85 | RAB9A (0.45) | MAPK1KMT2A | |
| SCHEMBL16600970 | 0.85 | RAB9A (0.45) | MAPK1KMT2A | |
| SCHEMBL16601135 | 0.85 | L3MBTL1 (0.46) | MAPK1KMT2A | |
| SCHEMBL16600857 | 0.84 | HRH3 (0.39) | MAPK1KMT2A | |
| SCHEMBL16600858 | 0.84 | HRH3 (0.39) | MAPK1KMT2A | |
| SCHEMBL16601210 | 0.81 | FAAH (0.37) | MAPK1KMT2A | |
| SCHEMBL16601212 | 0.81 | FAAH (0.37) | MAPK1KMT2A | |
| SCHEMBL16601126 | 0.74 | L3MBTL1 (0.47) | — | |
| SCHEMBL16600792 | 0.73 | L3MBTL1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | disclosed |