Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23922127 | 0.82 | CACNA1H (0.49) | CACNA1HALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11249172 | 0.79 | CARM1 (0.54) | ALDH1A1KDM1AMEN1TSHRKMT2A | |
| SCHEMBL14500308 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM1AMEN1TSHRKMT2A | |
| SCHEMBL7745202 | 0.77 | CACNA1H (0.45) | CACNA1HALDH1A1KDM1ATSHRKDM4E | |
| SCHEMBL4569276 | 0.76 | KDM1A (0.42) | ALDH1A1KDM1ATSHRKMT2AKDM4E | |
| SCHEMBL12607000 | 0.75 | MEN1 (0.44) | ALDH1A1KDM1AMEN1TSHRKMT2A | |
| SCHEMBL4054338 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM1AMEN1TSHRKMT2A | |
| SCHEMBL10245377 | 0.75 | CACNA1H (0.44) | CACNA1HALDH1A1KDM1AKDM4EMAPT | |
| SCHEMBL26748675 | 0.75 | CACNA1H (0.44) | CACNA1HSMN1; SMN2 | |
| SCHEMBL10192177 | 0.74 | CARM1 (0.56) | CACNA1HALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637492-B2 | Benzothiazole kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-05-02 | — | — | US | disclosed |
| US-9637492-B2 | Benzothiazole kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-05-02 | — | — | US | disclosed |
| US-8993580-B2 | Benzothiazole kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2015-03-31 | — | — | US | disclosed |