SCHEMBL7745202

SCHEMBL7745202

CN1CCN(CCNC(C)(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA1H O95180 1/20 0.45
CARM1 Q86X55 2/20 0.38
PRMT6 Q96LA8 2/20 0.38
PRMT8 Q9NR22 2/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ACE2 Q9BYF1 1/20 0.37
KDM1A O60341 1/20 0.36
CNR1 P21554 1/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
PAOX Q6QHF9 1/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
PRMT1 Q99873 1/20 0.33
KAT2B Q92831 1/20 0.33
SIGMAR1 Q99720 2/20 0.32
MC4R P32245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23922127 0.93 CACNA1H (0.49) CACNA1HCARM1PRMT6PRMT8ACE2
SCHEMBL7891824 0.87 PAOX (0.40) CACNA1HACE2PAOXALDH1A1KDM4E
SCHEMBL28631927 0.85 PAOX (0.43) CACNA1HPAOXALDH1A1SIGMAR1
SCHEMBL26748675 0.84 CACNA1H (0.44) CACNA1HCARM1PRMT6PRMT8ACE2
SCHEMBL10245377 0.84 CACNA1H (0.44) CACNA1HCARM1PRMT6PRMT8ACE2
SCHEMBL19961023 0.84 CARM1 (0.50) CACNA1HCARM1PRMT6PRMT8ACE2
SCHEMBL10192177 0.84 CARM1 (0.56) CACNA1HCARM1PRMT6PRMT8ALDH1A1
SCHEMBL28644525 0.84 PAOX (0.46) CACNA1HPAOXALDH1A1SIGMAR1
SCHEMBL12262499 0.83 CACNA1H (0.43) CACNA1HCARM1PRMT6PRMT8ACE2
SCHEMBL26581818 0.83 HDAC2 (0.36) CACNA1HCARM1PRMT6PRMT8HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113453784-B Method for removing acid gases from fluid streams 巴斯夫欧洲公司 2024-09-13 CN claimed
EP-3927450-B1 PROCESS FOR REMOVAL OF ACID GASES FROM A FLUID STREAM WITH A LIQUID ABSORBENT COMPRISING A PIPERAZINE RING BASF SE (DE) 2023-06-07 EP claimed
CN-113453784-A Process for removing acid gases from fluid streams 巴斯夫欧洲公司 2021-09-28 CN claimed
US-12138583-B2 Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring BASF SE (DE) 2024-11-12 US disclosed
CN-113453784-B Method for removing acid gases from fluid streams 巴斯夫欧洲公司 2024-09-13 CN disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
US-11833122-B2 Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases CALGENT BIOTECHNOLOGY CO., LTD. (TW) 2023-12-05 US disclosed
US-11834454-B2 Alkynylphenylbenzamide compounds and applications thereof SHENZHEN NEWDEL BIOTECH CO., LTD. (CN) 2023-12-05 US disclosed
US-11834454-B2 Alkynylphenylbenzamide compounds and applications thereof SHENZHEN NEWDEL BIOTECH CO., LTD. (CN) 2023-12-05 US disclosed
US-11834412-B2 Derivatives of aryl hydrocarbon receptor agonists AZORA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20090192177-A1 2-ARYL pyrrologpyrimidines for A1 and A3 receptors OSI PHARMACEUTICALS, INC. 2009-07-30 US disclosed
WO-2009074749-A2 NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2009-06-18 WO disclosed
US-20090082369-A1 Pyrrolo[2,3d]pyrimidine compositions and their use OSI PHARMACEUTICALS, INC. 2009-03-26 US disclosed
US-7504407-B2 Compounds specific to adenosine A1 and A3 receptors and uses thereof OSI PHARMACEUTICALS, INC. (US) 2009-03-17 US disclosed
US-20080280889-A1 Inhibitors of Akt Activity MERCK SHARP & DOHME CORP. 2008-11-13 US disclosed
US-7429574-B2 4-heterocyclo-pyrrolo[2,3d] pyrimidine compositions and their use OSI PHARMACEUTICALS, INC. (US) 2008-09-30 US disclosed
US-20080070936-A1 Compounds specific to adenosine A1 receptors and uses thereof OSI PHARMACEUTICALS, INC. 2008-03-20 US disclosed
US-7160890-B2 Compounds specific to adenosine A3 receptor and uses thereof OSI PHARMACEUTICALS, INC. (US) 2007-01-09 US disclosed
US-6680324-B2 4-AMINO-6-PHENYL-PYRROLO(2,3-D)PYRIMIDINE DERIVATIVES OSI PHARMACEUTICALS, INC. 2004-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834412-B2 Derivatives of aryl hydrocarbon receptor agonists AHR, ARNT, NR4A1 CACNA1H 3129/4885CARM1 546/4885PRMT6 1642/4885
US-20090192177-A1 2-ARYL pyrrologpyrimidines for A1 and A3 receptors ADORA3, ADORA1, ADORA2A CACNA1H 3216/4885CARM1 3615/4885PRMT6 2134/4885
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TP53, HRAS, KRAS CACNA1H 4499/4885CARM1 665/4885PRMT6 1432/4885
US-11834454-B2 Alkynylphenylbenzamide compounds and applications thereof ALK, NTRK1, ERBB2 CACNA1H 3537/4885CARM1 3029/4885PRMT6 1278/4885
US-20090082369-A1 Pyrrolo[2,3d]pyrimidine compositions and their use ADORA3, ADORA2A, ADORA1 CACNA1H 3993/4885CARM1 1094/4885PRMT6 552/4885
US-20080070936-A1 Compounds specific to adenosine A1 receptors and uses thereof ADORA1, ADORA2A, ADORA3 CACNA1H 1646/4885CARM1 2741/4885PRMT6 2203/4885
US-11833122-B2 Aminonaphthoquinone compounds for treatment and/or prevention of fibrosis diseases KEAP1, GOT2, COL1A1 CACNA1H 4104/4885CARM1 1397/4885PRMT6 567/4885
US-12138583-B2 Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring AVPR2, HRH2, SLC43A1 CACNA1H 2627/4885CARM1 1650/4885PRMT6 3019/4885
US-20080280889-A1 Inhibitors of Akt Activity AKT2, PIK3CA, AKT1 CACNA1H 4842/4885CARM1 2297/4885PRMT6 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.