Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 8/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978089 | 0.88 | TNF (0.39) | TNFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10018480 | 0.82 | PRMT1 (0.40) | POLBALDH1A1KDM4EHPGDPIN1 | |
| SCHEMBL16601633 | 0.81 | PRMT1 (0.39) | POLBALDH1A1KDM4EHPGDPRMT1 | |
| SCHEMBL16601609 | 0.76 | TDP1 (0.44) | POLBALDH1A1KDM4EHPGDPRMT1 | |
| SCHEMBL16601612 | 0.75 | PRMT1 (0.35) | POLBALDH1A1KDM4EHPGDPRMT1 | |
| SCHEMBL18348919 | 0.74 | MEN1 (0.43) | POLBALDH1A1KDM4EHPGDPIN1 | |
| SCHEMBL18351287 | 0.72 | PIN1 (0.37) | TNFPOLBALDH1A1KDM4EPIN1 | |
| SCHEMBL16656165 | 0.72 | CASP3 (0.41) | POLBALDH1A1KDM4EHPGDPIN1 | |
| SCHEMBL10018474 | 0.72 | PIN1 (0.36) | ALDH1A1HPGDPIN1PIN4NPC1 | |
| SCHEMBL16601613 | 0.70 | PRMT1 (0.40) | TNFPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |