SCHEMBL16601647

SCHEMBL16601647

CC(O)CNCCN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(CCNCC(C)O)C3=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.56
▸ HEXA P06865 5/20 0.50
▸ HEXB P07686 5/20 0.50
▸ OGA O60502 1/20 0.50
▸ SIRT1 Q96EB6 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ RGS12 O14924 1/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ PABPC1 P11940 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ TOP2A P11388 2/20 0.44
▸ DYRK3 O43781 1/20 0.42
▸ RPS6KB1 P23443 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656335 0.83 TERT (0.51) TERTHEXAHEXBOGASIRT1
SCHEMBL16601677 0.82 OGA (0.41) TERTHEXAHEXBOGASIRT1
SCHEMBL16866436 0.77 KDM4E (0.43) TERTSIRT1KDM4EMEN1RGS12
SCHEMBL16864815 0.73 L3MBTL1 (0.49) TERTKDM4EMEN1RGS12NPC1
SCHEMBL23957113 0.73 TERT (0.70) TERTHEXAHEXBOGASIRT1
SCHEMBL8397653 0.72 SIRT1 (0.61) TERTHEXAHEXBOGASIRT1
SCHEMBL16864784 0.71 KDM4E (0.43) TERTHEXAHEXBKDM4EMEN1
SCHEMBL16864780 0.71 KDM4E (0.43) TERTHEXAHEXBKDM4EMEN1
SCHEMBL16864776 0.70 NTRK1 (0.43) TERTHEXAHEXBKDM4EMEN1
SCHEMBL15712038 0.68 KDM4E (0.74) TERTHEXAHEXBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 — — US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 — — US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 — — US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 — — US disclosed
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