SCHEMBL16864815

SCHEMBL16864815

CC(O)CNN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(NCC(C)O)C3=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.49
▸ NPC1 O15118 2/20 0.49
▸ RAB9A P51151 2/20 0.49
▸ TERT O14746 6/20 0.40
▸ ALDH1A1 P00352 7/20 0.36
▸ KDM4E B2RXH2 4/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ RECQL P46063 2/20 0.36
▸ RGS12 O14924 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ PABPC1 P11940 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ PIN1 Q13526 1/20 0.36
▸ PIN4 Q9Y237 1/20 0.36
▸ HPGD P15428 2/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ APAF1 O14727 1/20 0.34
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16864776 0.91 NTRK1 (0.43) L3MBTL1NPC1RAB9ATERTALDH1A1
SCHEMBL16864773 0.86 NPC1 (0.38) L3MBTL1NPC1RAB9ATERTALDH1A1
SCHEMBL28084227 0.86 KMT2A (0.46) L3MBTL1RAB9AALDH1A1KDM4EKMT2A
SCHEMBL16864828 0.85 RAB9A (0.37) L3MBTL1NPC1RAB9ATERTALDH1A1
SCHEMBL16864819 0.83 ALDH1A1 (0.38) L3MBTL1NPC1RAB9AALDH1A1KDM4E
SCHEMBL16864829 0.82 KMT2A (0.39) L3MBTL1NPC1RAB9AALDH1A1KMT2A
SCHEMBL16864780 0.82 KDM4E (0.43) L3MBTL1NPC1RAB9ATERTALDH1A1
SCHEMBL16864784 0.82 KDM4E (0.43) L3MBTL1NPC1RAB9ATERTALDH1A1
SCHEMBL16864799 0.77 KCNJ1 (0.37) L3MBTL1NPC1RAB9AALDH1A1KMT2A
SCHEMBL11535555 0.77 L3MBTL1 (0.40) L3MBTL1NPC1RAB9ATERTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
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