SCHEMBL16864780

SCHEMBL16864780

CC(O)CNN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(CCSCCO)C3=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ RGS12 O14924 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ PABPC1 P11940 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ TERT O14746 6/20 0.40
▸ HEXA P06865 1/20 0.35
▸ HEXB P07686 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ HPGD P15428 1/20 0.34
▸ STAT3 P40763 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ TOP2A P11388 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16864815 0.82 L3MBTL1 (0.49) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL16864784 0.81 KDM4E (0.43) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL16864776 0.79 NTRK1 (0.43) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL15764209 0.76 KDM4E (0.44) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL16656199 0.74 KDM4E (0.46) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL16864773 0.73 NPC1 (0.38) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL16656203 0.72 KDM4E (0.44) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL16601647 0.71 TERT (0.56) KDM4EALDH1A1NPC1RAB9AMEN1
SCHEMBL28084227 0.70 KMT2A (0.46) KDM4EALDH1A1RAB9AMEN1LMNA
SCHEMBL4360907 0.70 NPC1 (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
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