SCHEMBL16601995 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MCL1	Q07820	5/20	0.50

▸	KMO	O15229	1/20	0.40

▸	FOLH1	Q04609	1/20	0.39

▸	AKR1C3	P42330	4/20	0.38

▸	AKR1C2	P52895	4/20	0.38

▸	RXRA	P19793	2/20	0.37

▸	RXRB	P28702	2/20	0.37

▸	DDT	P30046	1/20	0.37

▸	PTGER1	P34995	1/20	0.37

▸	TDP2	O95551	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16602004	0.92	MCL1 (0.52)	MCL1KMOFOLH1AKR1C3AKR1C2
SCHEMBL16601996	0.82	MCL1 (0.52)	MCL1TDP2
SCHEMBL16601985	0.80	MCL1 (0.45)	MCL1
SCHEMBL16602049	0.74	MCL1 (0.50)	MCL1
SCHEMBL16601999	0.74	KMO (0.56)	KMOFOLH1AKR1C3AKR1C2RXRA
SCHEMBL16602047	0.73	MCL1 (0.55)	MCL1
SCHEMBL16601994	0.73	MCL1 (0.49)	MCL1
SCHEMBL17014853	0.68	KMO (0.53)	KMOFOLH1AKR1C3AKR1C2RXRA
SCHEMBL2367407	0.68	MCL1 (1.00)	MCL1
SCHEMBL16602042	0.67	KMO (0.51)	KMORXRARXRBPTGER1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8993205-B2	Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus	CANON KABUSHIKI KAISHA (JP)	2015-03-31	—	—	US	disclosed