Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | DDT | P30046 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601995 | 0.92 | MCL1 (0.50) | MCL1KMOFOLH1AKR1C3AKR1C2 | |
| SCHEMBL16602008 | 0.83 | MCL1 (0.55) | MCL1TDP2 | |
| SCHEMBL16602012 | 0.81 | MCL1 (0.52) | MCL1AKR1C3AKR1C2ACMSD | |
| SCHEMBL16602011 | 0.78 | MCL1 (0.57) | MCL1 | |
| SCHEMBL16602007 | 0.77 | MCL1 (0.56) | MCL1RXRARXRB | |
| SCHEMBL16601985 | 0.75 | MCL1 (0.45) | MCL1 | |
| SCHEMBL16602019 | 0.75 | MCL1 (0.53) | MCL1 | |
| SCHEMBL16601996 | 0.74 | MCL1 (0.52) | MCL1TDP2 | |
| SCHEMBL14922765 | 0.71 | MCL1 (0.67) | MCL1 | |
| SCHEMBL29186265 | 0.71 | MEN1 (0.54) | KMOFOLH1AKR1C3AKR1C2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |