Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817931 | 0.87 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CIRAK4CA1 | |
| SCHEMBL1458318 | 0.83 | IRAK4 (0.40) | IRAK4CA1CA2CA7CA9 | |
| SCHEMBL677043 | 0.83 | MCHR1 (0.37) | IRAK4CA1CA2CA7CA9 | |
| SCHEMBL5412735 | 0.82 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CIRAK4ALDH1A1 | |
| SCHEMBL2069873 | 0.81 | MCHR1 (0.46) | ADRA2AADRA2BADRA2CIRAK4CA1 | |
| SCHEMBL17887315 | 0.79 | MCHR1 (0.44) | ADRA2AADRA2BADRA2CIRAK4CA1 | |
| SCHEMBL12514817 | 0.79 | GABRA1 (0.47) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL11919265 | 0.79 | DHODH (0.41) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL8371344 | 0.79 | IRAK4 (0.40) | ADRA2AADRA2BADRA2CIRAK4CA1 | |
| SCHEMBL27867050 | 0.77 | ALDH1A1 (0.42) | ADRA2AADRA2BADRA2CIRAK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364217-B2 | Chemical compounds | RESMAN AS (NO) | 2019-07-30 | — | — | US | disclosed |
| US-20160214930-A1 | CHEMICAL COMPOUNDS | RESMAN AS (NO) | 2016-07-28 | — | — | US | disclosed |
| US-20150094240-A1 | CHEMICAL COMPOUNDS | RESMAN AS (NO) | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214930-A1 | CHEMICAL COMPOUNDS | PTGES, PTGIS, PTGFR | ADRA2A 4447/4885ADRA2B 3965/4885ADRA2C 4107/4885 |
| US-20150094240-A1 | CHEMICAL COMPOUNDS | PTGES, PTGIS, PTGFR | ADRA2A 4447/4885ADRA2B 3965/4885ADRA2C 4107/4885 |
| US-10364217-B2 | Chemical compounds | PTGES, PTGIS, PTGFR | ADRA2A 4447/4885ADRA2B 3965/4885ADRA2C 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.