Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | APC | P25054 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661011 | 0.89 | ACE (0.48) | BACE1 | |
| SCHEMBL1662059 | 0.89 | CTSL (0.54) | CTSLCTSBCTSSCTSKOPRK1 | |
| SCHEMBL1661910 | 0.85 | CTSL (0.65) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1661176 | 0.85 | CTSL (0.65) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1663148 | 0.84 | APC (0.51) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1663151 | 0.83 | CTSL (0.44) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1663171 | 0.81 | CTSL (0.71) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL1661924 | 0.81 | CTSL (0.71) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL1660344 | 0.81 | CTSL (0.64) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1662038 | 0.81 | CTSL (0.64) | CTSLCTSBCTSSCTSKAPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |