Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APC | P25054 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663151 | 0.90 | CTSL (0.44) | APCCASP1CASP3CASP9CTSL | |
| SCHEMBL1661229 | 0.90 | ACE (0.51) | ACEAVPR1ANAALAD2BACE1BACE2 | |
| SCHEMBL19252727 | 0.87 | FOLH1 (0.47) | APCCASP1CASP3CASP9CTSL | |
| SCHEMBL1661910 | 0.84 | CTSL (0.65) | APCCASP1CASP3CASP9CTSL | |
| SCHEMBL1661176 | 0.84 | CTSL (0.65) | APCCASP1CASP3CASP9CTSL | |
| SCHEMBL1660926 | 0.84 | CTSL (0.56) | APCCASP1CASP3CASP9CTSL | |
| SCHEMBL1662059 | 0.83 | CTSL (0.54) | APCCASP1CASP3CASP9CTSL | |
| SCHEMBL1661011 | 0.79 | ACE (0.48) | ACEAVPR1AERAP2ERAP1LNPEP | |
| SCHEMBL1661066 | 0.79 | AVPR1A (0.44) | ACEAVPR1ANAALAD2 | |
| SCHEMBL1662080 | 0.79 | BACE1 (0.49) | AVPR1ANAALAD2BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |