Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.37 |
| ▸ | USP7 | Q93009 | 2/20 | 0.37 |
| ▸ | USP10 | Q14694 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993294 | 0.80 | KDM4E (0.42) | CLK1DYRK1ADYRK1BMAPK14ERN1 | |
| SCHEMBL21963090 | 0.74 | CA2 (0.41) | CLK1DYRK1ADYRK1BMAPK14ERN1 | |
| SCHEMBL6089271 | 0.69 | SLC9A1 (0.60) | CLK1DYRK1ADYRK1BL3MBTL1ALDH1A1 | |
| SCHEMBL3838638 | 0.65 | — | — | |
| SCHEMBL15041008 | 0.65 | GPR35 (0.64) | CLK1DYRK1ADYRK1BPNMTL3MBTL1 | |
| SCHEMBL5850753 | 0.65 | MAPT (0.68) | CLK1DYRK1ADYRK1BPNMTL3MBTL1 | |
| SCHEMBL17988510 | 0.65 | CLK1 (0.67) | CLK1DYRK1ADYRK1BL3MBTL1LMNA | |
| SCHEMBL2872059 | 0.64 | GSK3B (0.67) | CLK1DYRK1ADYRK1BERN1L3MBTL1 | |
| SCHEMBL16414464 | 0.64 | THRB (0.33) | L3MBTL1MAPTALDH1A1NPSR1TP53 | |
| SCHEMBL21963324 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015043364-A1 | BENZOXAZOLEOXAZINE KETONE COMPOUND AS BLOOD COAGULATION FACTOR XA INHIBITOR | 华北制药集团新药研究开发有限责任公司 | 2015-04-02 | — | — | WO | disclosed |