SCHEMBL16610065

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16599232	0.88	PTGS2 (0.57)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL22502979	0.86	PTGS2 (0.52)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL16610064	0.86	PTGS2 (0.51)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL4134522	0.84	PTGS2 (0.73)	PTGS2KDM4EHSD17B10LMNACYP1A2
	SCHEMBL17986294	0.81	PTGS2 (0.47)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL16610075	0.79	PTGS2 (0.46)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL16599463	0.78	PTGS2 (0.51)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL80532	0.75	LMNA (0.57)	KDM4EHSD17B10LMNAKMT2AMEN1
	SCHEMBL18020601	0.75	PTGS2 (0.53)	PTGS2CFDKDM4EHSD17B10LMNA
	SCHEMBL1162227	0.74	CFD (0.49)	PTGS2CFDKDM4EHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.